Quiz Case

Quiz Case 1

A N ASYMPTOMATIC 9-year-old girl with normal childhood development was referred for DNA sequence analysis of the RET proto-oncogene on chromosome 10. She was the daughter of a woman with multiple endocrine neoplasia syndrome type 2A (MEN-2A). Genetic testing revealed a mutation involving codon 618 of the RET proto-oncogene that changed the wild-type TGC codon to a TCC codon. Her mother and 6-ye...

Pathology Case Quiz 2

A N 86-YEAR-OLD WOMAN PRESENTED WITH a few months’ history of progressive fullness in the right side of her face along with localized discomfort in her right maxillary region. She denied any trauma, nasal obstruction, diplopia, neurologic deficits, dysphagia, odynophagia, voice changes, weight loss, cough, pulmonary symptoms, fever, or chills. She also denied any history of tobacco or alcohol u...

Quiz Case of the Month

Pathology quiz case: Plasmacytoid dendritic cell neoplasm

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that possesses a heterogenous clinical and immunophenotypic presentation. The current case report describes an interesting and unique presentation of BPDCN as a primary paranasal sinus tumor without evidence of cutaneous or systemic involvement. As such, the report further contributes to the ongoing debate reg...

Image of the month--quiz case.

A 68-YEAR-OLD MAN WAS ADMITTED TO THE hospital with fever, right loin pain, and right hip stiffness of 3 days’ duration. He has had 3 hospital admissions since February 2005 for right-sided psoas abscess. The abscess was treated with ultrasonographic-guided drainage twice, and 2 weeks before this admission, the patient had an open appendectomy through a Lanz incision with evacuation of the absc...